Status:

COMPLETED

ARDA Software for the Detection of mtmDR

Lead Sponsor:

Verily Life Sciences LLC

Collaborating Sponsors:

Google LLC.

Optos, PLC

Conditions:

Diabetic Retinopathy

Eligibility:

All Genders

22+ years

Brief Summary

This is a multicenter, observational study with primary endpoints to determine the sensitivity and specificity of two investigational software devices that detect the presence of more than mild diabet...

Eligibility Criteria

Inclusion

  • Documented diagnosis of Type I or Type II diabetes mellitus:
  • meet the criteria established by either the World Health Organization (WHO) or the American Diabetes Association (ADA)
  • Age 22 or older
  • Understand the study and volunteer to sign the informed consent

Exclusion

  • Self-reported visual symptoms and persistent blurred vision (greater than 24 hours); including vision loss that cannot be corrected (e.g. with eye glasses).
  • Diagnosed with macular edema, any known retinopathy, radiation retinopathy, or retinal vein occlusion.
  • History of laser treatment of the retina or injections into either eye, or any history of retinal surgery.
  • Scheduled to undergo the following surgeries before completion of the study imaging: cataract surgery (including any related follow-up procedures) or vitrectomy.
  • Currently participating in an interventional study.
  • Participant has a condition that, in the opinion of the investigator, would preclude participation in the study (e.g., unstable medical status including blood pressure or glycemic control, microphthalmia or previous enucleation, etc.).
  • Participant is contraindicated for imaging by fundus imaging system used in the study; e.g.
  • Participant is hypersensitive to light (side effect of medication or due to unknown etiology)
  • Participant has undergone photodynamic therapy (PDT)
  • Previous issues with dilation (angle closure, inability to dilate, allergy to dilation drops).
  • Known pregnancy or possibility of pregnancy

Key Trial Info

Start Date :

September 30 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 23 2022

Estimated Enrollment :

1012 Patients enrolled

Trial Details

Trial ID

NCT04905459

Start Date

September 30 2021

End Date

May 23 2022

Last Update

June 6 2022

Active Locations (13)

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Page 1 of 4 (13 locations)

1

Midwestern University

Glendale, Arizona, United States, 85308

2

NEA Baptist Clinic

Jonesboro, Arkansas, United States, 72404

3

Catalina Research Institute

Montclair, California, United States, 91763

4

Christie Clinic

Champaign, Illinois, United States, 61822