Status:

COMPLETED

Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura

Lead Sponsor:

Danish Headache Center

Conditions:

Headache, Migraine

Aura

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

To investigate the migraine inducing effect of levcromakalim in patients with migraine with aura.

Eligibility Criteria

Inclusion

  • Migraine with aura patients of both sexes.
  • 18-70 years.
  • 50-100 kg.

Exclusion

  • Headache less than 48 hours before the tests start
  • Daily consumption of drugs of any kind that investigator deems might affect study results or safety.
  • Pregnant or nursing women.
  • Cardiovascular disease of any kind, including cerebrovascular diseases.
  • Tension type headache (TTH) according to International Classification of Headache Disorders version 3 more than 5 times a month on average during the past year
  • Known cluster headache according to International Classification of Headache Disorders version 3.
  • Psychiatric disorder
  • Smoking or abuse of drugs or alcohol
  • Hypertension (systolic blood pressure \>150 mmHg and/or diastolic blood pressure \>100 mmHg) on day of inclusion.
  • Hypotension (systolic blood pressure \<90 mmHg and/or diastolic blood pressure \<50 mmHg) on day of inclusion.

Key Trial Info

Start Date :

September 29 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 16 2023

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT04905654

Start Date

September 29 2021

End Date

May 16 2023

Last Update

May 17 2023

Active Locations (1)

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1

Danish Headache Center

Glostrup Municipality, Copenhagen, Denmark, DK-2600

Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura | DecenTrialz