Status:

UNKNOWN

Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache

Lead Sponsor:

Cairo University

Conditions:

Headache

Eligibility:

FEMALE

18-45 years

Phase:

PHASE2

PHASE3

Brief Summary

We hypothesized that; intrathecal administration of neostgmine in spinal anesthesia may have a beneficial role in reduction of the incidence or severity of PDPH.

Detailed Description

Neostigmine will be administered in two different doses (10 \& 20 mic) in addition to 10mg bupivicaine intrathecally for cesarean section compared to control group where 10 mg bupivicaine in addition ...

Eligibility Criteria

Inclusion

  • Patients indicated for elective caesarean section surgery

Exclusion

  • Contraindications for regional anesthesia including local infection, hemorrhagic disorders, drug hypersensitivity, muscular disorders and central and peripheral neuropathy, and drug abuse history and addiction.

Key Trial Info

Start Date :

February 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2022

Estimated Enrollment :

274 Patients enrolled

Trial Details

Trial ID

NCT04905953

Start Date

February 1 2021

End Date

May 1 2022

Last Update

May 28 2021

Active Locations (1)

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1

Faculty of Medicine- Cairo University

Cairo, Egypt, 11562