Status:

COMPLETED

Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes

Lead Sponsor:

University of Missouri-Columbia

Conditions:

Exercise Intervention

Eligibility:

All Genders

18-35 years

Phase:

NA

Brief Summary

The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Detailed Description

The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Eligibility Criteria

Inclusion

  • Age 18-35 years
  • BMI: 25-45 kg/m2
  • Sedentary lifestyle
  • Consistent diet patterns
  • Weight-stable (\<4 kg change over the last 3 mo)
  • Willingness to adhere to resistance training protocol and not change diet
  • Non-smoker \>1 year or more

Exclusion

  • Disabilities preventing adherence to resistance training protocol
  • Recent start of medications that affect metabolism or appetite
  • Antibiotics
  • Diabetes
  • Drug therapy for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia
  • Uncontrolled hypertension and blood pressure ≥ 180/110
  • Gastrointestinal disease and/or bariatric surgery
  • Smoking
  • Illicit drug use
  • Pregnant or lactating individuals

Key Trial Info

Start Date :

May 19 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 30 2022

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT04906525

Start Date

May 19 2021

End Date

September 30 2022

Last Update

March 13 2023

Active Locations (1)

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1

University of Missouri

Columbia, Missouri, United States, 65211