Status:

ACTIVE_NOT_RECRUITING

H-reflex in Spastic Lower Limb Cryoneurotomy

Lead Sponsor:

Vancouver Island Health Authority

Conditions:

Muscle Spasticity

Eligibility:

All Genders

18-70 years

Brief Summary

Spasticity is a common complication after many upper motor neurone disorders. Many surgical techniques have been introduced for patients with refractory spasticity though they are not without peri-ope...

Detailed Description

Different surgical techniques, including muscle and tendon lengthening and neurotomy/neurectomy (surgical sectioning of a peripheral nerve) are reserved for patients with refractory spasticity. Cryon...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patient group:
  • Patients who will have cryoneurotomy as part of their standard treatment for spastic equinovarus foot in VGH spasticity multidisciplinary clinic
  • Adults 18-70 years of age (male and female)
  • Ability to attend testing sessions, comply with testing protocols and provide written informed consent.
  • Able to understand and complete study-related questionnaires (must be able to understand and speak English or have access to an appropriate interpreter as judged by the investigator).
  • Inclusion Criteria for healthy participants:
  • Any healthy participants with the age between 18 to 70. Over 70 will be excluded due to the expected natural alterations in electrophysiological parameters
  • Able to attend and comply with the testing protocols
  • Able to provide informed written consent
  • Able to understand and speak English or have access to an appropriate interpreter
  • Exclusion Criteria:
  • History of previous nerve procedures such as chemical neurolysis with alcohol, cryoneurotomy, any surgery of the tibial nerve.
  • Any other neurological pathology different from that responsible for the spasticity.

Exclusion

    Key Trial Info

    Start Date :

    December 15 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 1 2024

    Estimated Enrollment :

    60 Patients enrolled

    Trial Details

    Trial ID

    NCT04907201

    Start Date

    December 15 2020

    End Date

    November 1 2024

    Last Update

    June 14 2024

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Victoria General Hospital

    Victoria, British Columbia, Canada, V8Z 6R5