Status:
RECRUITING
Impact of Obesity on Post-operative Cognitive Dysfunction: Role of Adipose Tissue
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Obesity
Cognitive Impairment
Eligibility:
All Genders
60-99 years
Brief Summary
This research aims at describing the relationship between white adipose tissue inflammation and post-operative cognitive dysfunctions.The possible link between inflammatory cytokines secretions of the...
Detailed Description
The postoperative cognitive dysfunctions (POCD) are characterized by delirium and cognitive impairment. The delirium is defined by an acute altered attention with a fluctuating course. The post-operat...
Eligibility Criteria
Inclusion
- patient about to receive a hip arthroplasty under general anesthesia, elective cardiac surgery with cardiopulmonary bypass,
- patient with a MMSE score \> or = 20(/30),
- patient able to give informed consent
Exclusion
- emergency surgery, or surgery in a septic context,
- patient with a known dementia or altered MMSE score (under 20)
Key Trial Info
Start Date :
September 21 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 21 2025
Estimated Enrollment :
408 Patients enrolled
Trial Details
Trial ID
NCT04907565
Start Date
September 21 2021
End Date
September 21 2025
Last Update
December 11 2024
Active Locations (1)
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1
Purpan University Hospital
Toulouse, France, 31059