Status:
UNKNOWN
Different Modes of Isotonic Exercises for Knee Osteoarthritis
Lead Sponsor:
Prince Sultan Military College of Health Sciences
Collaborating Sponsors:
King Fahd Military Medical Complex
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
40-65 years
Phase:
NA
Brief Summary
This is a randomized controlled trial examining and compare the effects of open and closed kinetic chain exercises on pain, function, and cartilage synthesis and degradation biomarkers after an eight-...
Detailed Description
Design and Subjects: A prospective, active control, three-parallel-group, assessor-blinded, randomized controlled trial. A sample of 120 subjects will be recruited and randomly assigned to one of thre...
Eligibility Criteria
Inclusion
- ≥40 years of age;
- having knee pain;
- having at least three of the following additional symptoms: a-morning stiffness ≤ 30 minutes, b-crepitation, c-bone margin tenderness, d-bony enlargement or e-no palpable warmth;
- willing to provide informed consent
Exclusion
- Knee joints showing Kellgren and Lawrence (K-L) grades 1 or 4;
- rheumatoid arthritis;
- serious pathological conditions (inflammatory arthritis and malignancy); total or partial arthroplasty of the affected knee joint, or on a waiting list for joint replacement surgery;
- recent surgical procedure of the lower extremities in the previous 6 months;
- uncontrolled hypertension and unstable cardiovascular problems that could subject the participant to increased risk with exercise and physical exertion;
- physical incapability to safely perform exercises, walking or stationary cycling, as in debilitating visual defects, neurological problems, exaggerated low back pain, advanced osteoporosis, and inability to walk 10 meters without an assistive device;
- use of prescribed analgesics, corticosteroid or analgesic injection intervention for knee pain within the previous 30 days;
- lack of clear comprehension of study procedures or inability to comply with instructions;
- stated inability to attend or complete the proposed course of intervention and follow-up schedule.
Key Trial Info
Start Date :
August 21 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2023
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04909086
Start Date
August 21 2021
End Date
June 1 2023
Last Update
September 30 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
King Fahd Military Medical Complex
Dammam, Saudi Arabia