Status:
COMPLETED
Pupil Dynamics and Color Vision for the Detection of Eye Diseases
Lead Sponsor:
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Collaborating Sponsors:
Streetlab
Conditions:
Retinitis Pigmentosa
Leber's Hereditary Optic Neuropathy
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The development of new oculometry techniques allows fine and dynamic measurements of pupillary diameter and use in routine clinical practice. The preliminary results obtained with innovative devices ...
Detailed Description
This is a single-head study that will take place at the National Ophthalmology Hospital Center (CHNO) and the Vision Institute (Streetlab) and the total duration of the study is 24 months . It is pla...
Eligibility Criteria
Inclusion
- \- Patients with an understanding of the French language to ensure a perfect understanding of the instructions during evaluations and documents relating to their involvement in the study.
- Visually impaired volunteers:
- Patients must have one of three conditions: Retinitis Pigmentosa, Stargardt disease, Leber optic neuropathy.
- Healthy volunteers:
- Visual acuity of both corrected eyes (glasses) should be higher or equal 8/10th and a normal visual field.
- Patients should not wear contact lenses (which may interfere with the recording of the pupil and eye movements)
Exclusion
- Pregnant or lactating women will not be able to participate in this research.
- Participants should not be unable to personally consent.
- Subjects should not participate in another clinical trial that may interfere with this research.
- Inability to personally consent.
- Subjects should not present with degenerative diseases or any other disease that could interfere with the evaluations planned during this study.
- The subject follows a drug treatment which can cause visual disturbances, changes in pupillary kinetics or cognitive disturbances.
- Secondary exclusion criteria (at the end of the inclusion visit):
- Visually impaired subjects and controls for which calibration is not feasible.
- Patients and control subjects having difficulty maintaining visual fixation.
- Patients and subjects wearing corrective lenses making it impossible to record oculomotor activity with an infrared camera oculometer.
Key Trial Info
Start Date :
March 22 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 22 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04909398
Start Date
March 22 2018
End Date
May 22 2019
Last Update
June 1 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Centre Hospitalier National D'Ophtalùmologie des Quinze-Vingts
Paris, France, 75012