Status:

COMPLETED

Glutamine Supplementation and Short-term Mortality in Covid-19

Lead Sponsor:

Assiut University

Conditions:

Covid19

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The aim of this study is to investigate the effect of parenteral L-Glutamine supplementation added to enteral nutrition on short-term ICU mortality (7 days) in Covid-19 diseased patients.

Detailed Description

A written informed consent will be taken from the patients or their relatives. Patients with diagnosis of covid-19 with enteral nutrition will be enrolled. Patients will be randomly assigned to receiv...

Eligibility Criteria

Inclusion

  • Diagnosis of covid-19 diseased patients admitted to the ICU with enteral nutrition.

Exclusion

  • Renal failure (creatinine \>180 mmol/l)
  • Hepatic failure (bilirubin \>40 mmol/l, alanine aminotransferase \>100 U/l and aspartate aminotransferase \>100 U/l)
  • Severe neutropenia (\<500 cells/mm3)
  • Patients receiving cytotoxic, radiation and/or steroid therapy
  • Hemodynamic instability

Key Trial Info

Start Date :

May 30 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 30 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04909905

Start Date

May 30 2021

End Date

October 30 2021

Last Update

November 5 2021

Active Locations (1)

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1

Omar Soliman

Asyut, Assuit, Egypt, Assuit universi