Status:

COMPLETED

Electromyographic Calibration Guided by Depth of Anesthesia

Lead Sponsor:

University Hospital Ulm

Collaborating Sponsors:

Technical University of Munich

Conditions:

Neuromuscular Blockade

Eligibility:

All Genders

18+ years

Brief Summary

The goal of the CELESTE study is to evaluate whether calibration of EMG is needed for reliable interpretation of neuromuscular function and if so, to identify the minimal necessary depth of anesthesia...

Detailed Description

Neuromuscular monitoring is used to document neuromuscular function intra-operatively. Failure to restore neuromuscular function prior to extubation results in residual neuromuscular blockade which is...

Eligibility Criteria

Inclusion

  • signed informed written consent
  • BMI 17.5-30 kg/m\^2
  • ASA \<= 3
  • supine positioning during surgery with intraoperative access to both arms
  • absence of allergy to muscle relaxants and reversal agents
  • absence of neuromuscular disease

Exclusion

  • ambulatory patients for whom discharge is planned within 12 hours of anaesthesia
  • patients undergoing minor surgical
  • procedures scheduled outside the operating room
  • patients who are endotracheally intubated prior to surgery
  • pregnancy
  • indication for rapid sequence induction
  • patients undergoing arm surgery
  • patients with preceding injuries impairing muscle or nerve function of the arm (e.g., finger amputation)

Key Trial Info

Start Date :

January 16 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 31 2023

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT04911088

Start Date

January 16 2022

End Date

May 31 2023

Last Update

January 25 2024

Active Locations (1)

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1

University Hospital Ulm

Ulm, Baden-Wurttemberg, Germany, 89073