Status:

COMPLETED

Neuroendocrine Changes in Cervical Spinal Manipulation and Mobilization Non-specific Mechanical Neck Pain

Lead Sponsor:

Loma Linda University

Conditions:

Neck Pain

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The aim for this graduate student research project is to determine if cervical spinal mobilization releases similar neuropeptides and endogenous hormones as compared to cervical spinal manipulation an...

Detailed Description

* Participants will be completing three standardized questionnaires: The Neck Disability Index (NDI), Numeric Pain Rate Scale (NPRS), and the Global Ration of Change (GROC). These self-rated questionn...

Eligibility Criteria

Inclusion

  • . Subjects will be healthy male and females between 18 to 60 years of age.
  • . Resting neck pain ≤ 30 days that is mechanical in nature without radiating pain below shoulder.
  • . Neck Disability Index ≥ 10/50.
  • . Negative Upper Cervical instability tests such as Sharper-Purser test, Alar ligament test and Transverse ligament test.

Exclusion

  • . Cervical Arterial Dysfunctions.
  • . Serious medical conditions (CA, spinal cord injury).
  • . History of instability disorders (History of neck injury, surgery, fractures, osteoporosis, arthritis, ankylosing spondylitis).
  • . Neurological conditions (Nerve root compression, central nervous system involvement, myelopathy, fibromyalgia.
  • . Endocrine dysfunctions (Autoimmune-related diseases, adrenal gland pathology, systematic metabolic disorders).
  • . Pregnancy/Lactating/Postpartum.
  • . Pending legal action regarding their neck pain.

Key Trial Info

Start Date :

June 17 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 10 2023

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04911608

Start Date

June 17 2021

End Date

January 10 2023

Last Update

January 20 2023

Active Locations (1)

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Loma Linda University

Loma Linda, California, United States, 92350