Status:

COMPLETED

Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise

Lead Sponsor:

Hacettepe University

Conditions:

Low Back Pain

Eligibility:

All Genders

20-55 years

Phase:

NA

Brief Summary

The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits. Patients...

Detailed Description

The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits. Patients...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patients with disc herniation:
  • Diagnosis of disc herniation (protrusion, extrusion, sequestered disc)
  • not an indication for lumbar disc herniation surgery
  • for patients with neurological deficits, loss of strength, decrease in DTRs, loss of sensation and at least one positive SLR test and presence of radicular pain
  • pain intensity of VAS ≥ 3
  • male and female patients between the ages of 20-55
  • Inclusion Criteria for heathy people
  • not having low back pain complaints in the past
  • female and male healthy individuals between the ages of 20-55
  • Exclusion Criteria:
  • systemic or inflammatory disease
  • pregnant or breastfeeding women
  • surgery of lumbar region
  • fracture of lumbar vertebrae
  • lumbar scoliosis
  • medication use for psychiatric disorders
  • tumor
  • allergy
  • neurological disease
  • alcohol-drug use
  • generalized musculoskeletal pain

Exclusion

    Key Trial Info

    Start Date :

    July 30 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 30 2024

    Estimated Enrollment :

    111 Patients enrolled

    Trial Details

    Trial ID

    NCT04912388

    Start Date

    July 30 2021

    End Date

    July 30 2024

    Last Update

    October 2 2024

    Active Locations (1)

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    Faculty of Physiotherapy and rehabilitation

    Ankara, Altındağ, Turkey (Türkiye), 06030