Status:

COMPLETED

Facilitating Patient Communication During Noninvasive Ventilation

Lead Sponsor:

University of Utah

Collaborating Sponsors:

National Institute of Nursing Research (NINR)

Axon Medical, Inc.

Conditions:

Noninvasive Ventilation

Speech Intelligibility

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Assessing speech intelligibility in a pilot study of patients speaking with a mask microphone while being treated with standard of care non-invasive ventilation. This is a feasibility study to test th...

Detailed Description

We will conduct a prospective feasibility study to evaluate speech intelligibility of 10 patients (target distribution of gender: 5 males, 5 females) undergoing standard of care, clinically indicated ...

Eligibility Criteria

Inclusion

  • Age greater than or equal to 18 years
  • Currently hospitalized
  • Awake and able to attempt communication
  • Respiratory failure requiring non-invasive ventilatory support
  • Positive Inspiratory Pressure (PIP) less than or equal to 20 cm H2O
  • Positive End Expiratory Pressure (PEEP) less than or equal to 10 cm H2O
  • FiO2 less than or equal to 0.60
  • Clinical attending physician believes it is safe for the patient to participate
  • Able to consent o If patient cannot consent on the basis of difficulty in being heard and asking questions (as in fact may occur with NIV, a key assumption of this study), then assent will be obtained from the patient with informed consent obtained from a legally authorized representative.

Exclusion

  • Tachypnea with RR \> 35
  • Increase in PIP, PEEP or FiO2 over the last 2 hours
  • Known to be delirious (clinically obtained CAM score that is positive)
  • Prisoner

Key Trial Info

Start Date :

October 11 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 9 2022

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04912544

Start Date

October 11 2021

End Date

May 9 2022

Last Update

August 1 2022

Active Locations (1)

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1

University of Utah

Salt Lake City, Utah, United States, 84112