Status:
COMPLETED
The Senstivity and Specificity of Using Salivary miRNAs in Detection of Malignant Transformation of Oral Lesions.
Lead Sponsor:
Cairo University
Conditions:
Oral Premalignant Lesions
Eligibility:
All Genders
35-70 years
Brief Summary
Due to cancer is a leading cause of death world wide , we will coduct the study to evaluate the diagnostic accuracy of using salivary miRNAs (412,512) from the salivary extracellular vesicles (index t...
Detailed Description
our study is a case control study,we will coduct our study to evaluate specificity and sensitivity of using salivary extracellular vesicles miRNAs (412,512) in detection of malignant transformation in...
Eligibility Criteria
Inclusion
- Clinically evident lesions as morphologically altered tissue noted at conventional visual tactile examination
- Clinically evident suspicious lesions which are morphologically altered tissue noted at comprehensive visual ductile examination ( CVTE) with a definitive diagnosis of a potentially malignant disorders (PMD) or even a malignant disorder to be a distinct possibly.
- Healthy subjects presenting no clinically detectable oral lesions matched for age, gender, and risk factors will recruited as controls.
Exclusion
- .\<18 years of age.
- pregnant or breast feeding. .psychiatrically or mentally unstable.
Key Trial Info
Start Date :
June 5 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 7 2020
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT04913545
Start Date
June 5 2019
End Date
August 7 2020
Last Update
June 9 2021
Active Locations (1)
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1
Dentistry
Cairo, Egypt