Status:
COMPLETED
Mechanisms Underlying Long-term Fatigue and Exercise Intolerance Following COVID-19
Lead Sponsor:
University College, London
Conditions:
COVID-19
Eligibility:
All Genders
18+ years
Brief Summary
The MEXICO study is an observational study that aims to identify underlying mechanisms contributing to exercise intolerance in the presence of persistent COVID-19 symptoms (Long COVID).
Detailed Description
Persistent symptoms of fatigue and severe exercise intolerance have been observed in some patients following infection with CoV-2. Termed 'Long COVID', these symptoms may persist for months after the ...
Eligibility Criteria
Inclusion
- Serological or clinical diagnosis of CoV-2 infection
- Ability to provide written informed consent.
Exclusion
- \< 18 years old.
- Considered a vulnerable adult
- Participant unwilling to consent
- Terminal illness or severe comorbidities affecting attendance or study investigations
- Pregnancy
- If the participant is not willing to give their consent for a clinical advisor to contact them if necessary
- Inability or presence of a contra-indication for exercise testing
- Chronic oral corticosteroid use (e.g. any maintenance dose of oral steroid, 4 or more course of oral steroid in previous 12 months, but not including prescription of dexamethasone during the acute episode of COVID-19, as long as that has been discontinued).
Key Trial Info
Start Date :
May 7 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 17 2023
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT04914754
Start Date
May 7 2021
End Date
January 17 2023
Last Update
May 16 2023
Active Locations (1)
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1
University College London
London, United Kingdom, WC1E6HX