Status:
COMPLETED
The Antihypertensive Effect of Remote Ischemic Conditioning (RIC-HTN).
Lead Sponsor:
Capital Medical University
Collaborating Sponsors:
Peking University Care Health Management Center
The 306 Hospital of People's Liberation Army
Conditions:
Hypertension,Essential
Prehypertension
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
This study intends to further reveal the antihypertensive effect of LRIC and explore its potential mechanisms.
Detailed Description
Stroke is the second-leading cause of death in the world and the leading cause of death in China. The estimated lifetime risk of stroke for those aged 25 years old and above is 24.9% worldwide and 39....
Eligibility Criteria
Inclusion
- Aged 50-80 years；
- Office blood pressure ≥130/80mmHg and\<160/100mmHg; and 24-h ambulatory systolic/diastolic blood pressure ≥125/75mmHg;
- Never taking antihypertensive drugs or have stopped taking antihypertensive drugs for more than one month;
- Do not receive any antihypertensive drugs during the research;
- Informed consent obtained from the subjects or their legally authorized representative.
Exclusion
- Secondary hypertension;
- Patients who are taking antihypertensive drugs regularly;
- Patients with contraindication for remote ischemic conditioning, such as vascular injury, soft tissue injury, orthopedic injury, or arm infection;
- Patients with bleeding disorder;
- Patients with atrial fibrillation or other severe arrhythmias；
- Patients with prior myocardial infarction or stroke；
- Patients with serious or unstable medical condition, such as severe liver or kidney dysfunction, heart failure, respiratory failure, malignant tumors, or autoimmune diseases;
- Participation in another device or drug trial simultaneously;
- Patients who are not suitable for this trial considered by researchers for other reasons.
Key Trial Info
Start Date :
June 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2022
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT04915313
Start Date
June 15 2021
End Date
August 1 2022
Last Update
November 10 2022
Active Locations (3)
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1
Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100053
2
Peking University Care Health Management Center
Beijing, Beijing Municipality, China, 100080
3
The 306 Hospital of People's Liberation Army
Beijing, Beijing Municipality, China, 100101