Status:

RECRUITING

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3

Lead Sponsor:

Virginia Commonwealth University

Conditions:

Peripheral Vascular Diseases

Eligibility:

All Genders

18-35 years

Phase:

NA

Brief Summary

The purpose of this research study is to examine the effect of various forms of exercise training on blood vessel function in healthy individuals as well as individuals with mental health disorders (p...

Detailed Description

Study #3 is made up of five sessions done on five separate days and the entire study can be completed in as little as 14 weeks. All testing sessions will take place at the Exercise Physiology Research...

Eligibility Criteria

Inclusion

  • apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease
  • for PTSD group, a score of ≥ 33 on PCL-5 checklist
  • for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist
  • for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist

Exclusion

  • taking medications that could influence cardiovascular function
  • current smokers who have recently quit smoking
  • illicit drug use or excessive alcohol consumption
  • pregnant women
  • significant calorie restriction or vitamin/mineral deficiencies
  • limited English proficiency

Key Trial Info

Start Date :

January 24 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 28 2026

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT04916340

Start Date

January 24 2022

End Date

February 28 2026

Last Update

December 24 2025

Active Locations (1)

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1

Virginia Commonwealth University

Richmond, Virginia, United States, 23298