Status:
TERMINATED
iPACK Block With Dexamethasone For Total Knee Replacement
Lead Sponsor:
University of California, San Diego
Conditions:
Knee Osteoarthritis
Acute Pain
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Comparing the pain control outcomes for patients undergoing total knee arthroplasty (TKA) with either: 1) adductor canal single shot injection plus placebo iPACK injection or 2) adductor canal single ...
Detailed Description
This will be a single-center (UCSD), randomized blinded investigation. Enrollment. Consenting adults undergoing TKA will be offered enrollment. Study inclusion will be proposed to eligible patients p...
Eligibility Criteria
Inclusion
- Having total knee arthroplasty at UC San Diego
- Plan to receive single shot adductor canal injection preoperatively
- Plan to receive spinal anesthetic with or without sedation for TKA surgery
Exclusion
- Pregnancy
- Inability to communicate with anesthesia provider and/or investigators
- Severe renal, hepatic, cardiac disease
- Chronic high-dose opioid use (defined as daily use for more than 4 weeks prior to surgery of at least the equivalent of 20 mg oxycodone)
- BMI \> 45 kg/m2
- Allergy to study medications (lidocaine, bupivacaine)
- Incarceration
Key Trial Info
Start Date :
June 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 7 2022
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT04917055
Start Date
June 7 2021
End Date
June 7 2022
Last Update
November 7 2023
Active Locations (1)
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1
University of California, San Diego
San Diego, California, United States, 92103