Status:
COMPLETED
Effectiveness of Compression Stocking on Overnight Fluid Shift in Obstructive Sleep Apnoea Patients
Lead Sponsor:
Khoo Teck Puat Hospital
Conditions:
Obstructive Sleep Apnea
Eligibility:
All Genders
30-65 years
Phase:
NA
Brief Summary
Overnight rostral fluid shift is one of the contributing factors for worsening obstructive sleep apnoea (OSA). Fluid shift has been recognized to play a role in the pathophysiology of sleep apnoea. Pr...
Eligibility Criteria
Inclusion
- Aged 30 years old to 65 years old.
- Either STOP-Bang score of ≥3 or Epworth sleepiness scale indicating mild excessive daytime sleepiness to severe excessive daytime sleepiness (11-24 points).
- Has pre-existing diabetes mellitus and/or hypertension and is on medication.
- Ability to provide informed consent.
- Not working night shift.
Exclusion
- Significant arterial disease due to the risk of limb ischaemia and necrosis.
- Not pregnant and not planning to get pregnant before the end of the study.
- History of psychiatric disease.
- Patient who are on wheelchair.
- Patient who has cardiac failure and or stroke.
- Patient who has end-stage renal failure. Estimated glomerular filtration rate \<15ml/min/1.73m2 or on renal replacement therapy i.e. dialysis or renal transplant.
- Patient who has liver disease.
- Patient who are on pacemaker, and metal implants.
- Patient who are on CPAP treatment for OSA.
- Patient who are illiterate.
- Medications which affect fluid balance or level of consciousness (e.g. diuretics, non- steroidal anti-inflammatory drugs (NSAIDS), corticosteroids, sedatives, opiates) at any time during the study.
Key Trial Info
Start Date :
August 28 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 27 2022
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT04917094
Start Date
August 28 2021
End Date
December 27 2022
Last Update
April 10 2023
Active Locations (1)
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1
Khoo Teck Puat Hospital
Singapore, Singapore, 768828