Status:
COMPLETED
Post-Operative Acute Pancreatitis After Pancreaticoduodenectomy
Lead Sponsor:
Azienda Ospedaliera Universitaria Integrata Verona
Conditions:
Acute Pancreatitis
Pancreatic Fistula
Eligibility:
All Genders
18+ years
Brief Summary
The occurrence of post-pancreatectomy acute pancreatitis (PPAP) can critically impact outcomes after pancreaticoduodenectomy. Although diagnosing a PPAP can be challenging, its identification appears ...
Detailed Description
The occurrence of an acute inflammatory process of the pancreatic parenchyma after pancreatic resections has been reported in the literature, but the actual existence of a clinically evident post-panc...
Eligibility Criteria
Inclusion
- Male and females ≥ 18 years;
- Scheduled for elective PD;
- ASA score \< 4;
- High-quality preoperative cross-sectional imaging of the abdomen performed roughly within one month before surgery;
- Upfront or after neoadjuvant therapy surgery is allowed;
- Ability of the subject to understand the character and individual consequences of the clinical trial;
- Written informed consent.
Exclusion
- Patients undergoing emergency surgery;
- Patients with high serum pancreatic amylase or lipase before surgery;
- Chronic use of steroids;
- Informed consent withdrawal;
- Pancreaticogastrostomy (PG);
- Use of octreotide analogs;
- Inability to perform the resection for any reason;
- Total or distal pancreatectomy;
- Need to extend the resection to the pancreas body for any reason.
- Inability to undergo MRI because of contraindications (e.g. claustrophobia, presence of non-MRI-compatible metal implants)
Key Trial Info
Start Date :
April 10 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2021
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT04917172
Start Date
April 10 2019
End Date
June 30 2021
Last Update
October 21 2022
Active Locations (1)
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1
Verona University Hospital
Verona, VR, Italy, 37134