Status:

UNKNOWN

Thromboelastographic Profile in Healthy Newborns and Infants of Diabetic Mothers Using TEG6s

Lead Sponsor:

Arkansas Children's Hospital Research Institute

Conditions:

Thromboelastography

Coagulation; Fetus or Newborn

Eligibility:

All Genders

Up to 2 years

Brief Summary

Thromboelastography (TEG) is a laboratory technique used to examine the process of clot formation and degradation by measuring and reporting the kinetic changes, the rate of clot formation, clot stren...

Detailed Description

Thromboelastography (TEG), is a laboratory technique used to examine the process of clot formation and degradation by measuring and reporting the kinetic changes, the rate of clot formation, clot stre...

Eligibility Criteria

Inclusion

  • Control Group: Healthy term neonates
  • Infants born at 37 weeks gestational age or greater born to mothers of any age with uncomplicated pregnancies
  • Comparison Group: Term infants of diabetic mothers
  • Infants born at 37 weeks gestational age or greater to mothers of any age with gestational diabetes or Type 1 or Type 2 diabetes, managed with either diet or insulin

Exclusion

  • For Both Groups:
  • Infants \<37 weeks gestational age
  • Multiple gestation pregnancies
  • Maternal thrombocytopenia
  • Known fetal anomalies
  • Known maternal blood clotting disorders or history of thrombosis
  • Known family history of clotting disorders
  • Chorioamnionitis (diagnosed prior to delivery)
  • For "Healthy Term Neonates"
  • Intrauterine growth restriction
  • Gestational hypertension, chronic hypertension, pre-eclampsia, and/or eclampsia
  • Any other major complication of pregnancy or major medical history

Key Trial Info

Start Date :

August 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2023

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04917965

Start Date

August 1 2021

End Date

June 30 2023

Last Update

July 23 2021

Active Locations (1)

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1

Arkansas Children's Hospital

Little Rock, Arkansas, United States, 72202