Status:

UNKNOWN

Hospital Management and 1-year Outcome of Patients Aged 70 Years and Older With Severe COVID-19

Lead Sponsor:

Centre Hospitalier le Mans

Conditions:

COVID-19

Elderly Patient

Eligibility:

All Genders

70+ years

Brief Summary

SARS-COV-2 infection can progress to acute respiratory distress syndrome and require hospitalization in the ICU in 5-20% of affected patients. Age is a major risk factor for developing a severe form a...

Eligibility Criteria

Inclusion

  • age ≥ 70 years on admission to hospital
  • diagnosis of SARS-CoV-2 infection defined by a positive RT-PCR test
  • medical or critical care hospitalisation between 1 July 2020 and 31 August 2021
  • who experienced severe hypoxaemic acute respiratory failure defined as at least 4L/min of oxygen during hospitalisation

Exclusion

  • Oxygen therapy \< 4L/min during hospitalisation
  • Mc Cabe score 3 (chronic disease fatal at 1 year such as stage IV heart failure, ventilated respiratory failure, metastatic cancer, Child C cirrhosis)
  • dementia or cognitive disorders before hospitalisation reported in the medical record
  • patient GIR 1 to 4 before hospitalisation reported in the medical file or deduced from the description of the lifestyle
  • patient with an ADL score \< 4 before hospitalisation reported in the medical record or deduced from the description of lifestyle
  • patient living in EHPAD before hospitalisation
  • non-French speaking patient
  • patient under guardianship or curatorship
  • refusal to participate in the study for patients surviving 1 year or refusal by a family member or trusted person

Key Trial Info

Start Date :

January 4 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2023

Estimated Enrollment :

450 Patients enrolled

Trial Details

Trial ID

NCT05184166

Start Date

January 4 2022

End Date

September 1 2023

Last Update

January 24 2022

Active Locations (1)

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1

Centre Hospitalier Du Mans

Le Mans, France, 72000