Status:

UNKNOWN

The Effect of Dietary Intervention on Endothelial Glycocalyx in Psoriasis

Lead Sponsor:

University of Athens

Conditions:

Psoriasis

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The food supplement Endocalyx is considered to support the endothelial glycocalyx integrity by supplying sulfated polysaccharides, anti-oxidant enzymes and additional substrates for glycocalyx synthes...

Detailed Description

Sixty patients with psoriatic disease, who are referred to the outpatient psoriasis clinic of the Attikon University Hospital, will be randomized to receive food supplement Endocalyx (4 capsules per d...

Eligibility Criteria

Inclusion

  • Caucasian patients with psoriatic disease (plaque-type psoriasis or psoriatic arthritis)
  • Body mass index ≥18.5 Kg/m2
  • If female, patients must be non-pregnant and non-breastfeeding

Exclusion

  • History of acute coronary syndrome. Coronary artery disease will be excluded by a clinical history, examination and electrocardiogram.
  • Moderate or severe valve disease
  • Primary cardiomyopathies
  • Chronic obstructive pulmonary disease
  • Asthma
  • Chronic kidney disease
  • Liver failure
  • Malignancies

Key Trial Info

Start Date :

November 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 30 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05184699

Start Date

November 1 2022

End Date

January 30 2024

Last Update

May 16 2023

Active Locations (1)

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1

Attikon University Hospital

Athens, Attica, Greece, 12462