Status:
COMPLETED
Blueberries and Exercise Inflammation
Lead Sponsor:
Appalachian State University
Conditions:
Muscular Injury
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if 2-weeks supplementation with blueberries (1 cup/day) compared to placebo can mitigate muscle soreness and damage, and improve inflammation resolution and m...
Detailed Description
Participants will be randomized to the blueberry or placebo groups. The parallel group design is being utilized in this study because of the "repeat exercise bout" effect (i.e., post-exercise muscle d...
Eligibility Criteria
Inclusion
- Male or female, ages 18-50 years.
- Non-smoker.
- Body mass index less than 18.5-30 kg/m2 (not obese).
- Not engaged in regular resistance training (less than 3 sessions per week).
- Agree to train normally, maintain weight, and avoid the regular use of protein supplements, large-dose vitamin and mineral supplements, herbs, and medications that influence inflammation and immune function (especially Advil, Motrin, aspirin, and similar anti-inflammatory drugs) for the duration of the study. (Participant will review supplement and medication use with the Research Manager during orientation).
- Agree to avoid consuming all berries including blueberries, raspberries, and strawberries.
- Agree to consume no more than an average of five servings per day of vegetables and fruit.
- Categorized as "low risk" using the American College of Sports Medicine screening questionnaire.
- Generally healthy and without chronic disease including cardiovascular disease (e.g., heart disease, stroke), cancer, type 1 and 2 diabetes, rheumatoid arthritis.
Exclusion
- Inability to comply with study requirements.
- Engaged in regular resistance training (3 or more sessions per week, on average).
- Body weight below 110 pounds.
- Pregnant or breastfeeding.
- Any other concurrent condition which, in the opinion of the primary investigator (PI), would preclude participation in this study or interfere with compliance.
- Current diagnosis of cardiovascular disease, diabetes, or cancer (except for non-melanoma skin cancer).
- History of allergic reactions to blueberry ingestion.
- Postmenopausal.
Key Trial Info
Start Date :
December 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 15 2022
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT05184855
Start Date
December 1 2021
End Date
August 15 2022
Last Update
January 25 2023
Active Locations (1)
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1
Appalachian State University Human Performance Lab, North Carolina Research Campus
Kannapolis, North Carolina, United States, 28081