Status:
RECRUITING
Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness
Lead Sponsor:
Johannes Gutenberg University Mainz
Conditions:
Hemodynamic Instability
Eligibility:
All Genders
18-80 years
Brief Summary
The purpose of this study is to assess respiratory variation of carotid doppler peak velocity (∆CDPV) for prediction of fluid responsiveness during major abdominal surgery.
Detailed Description
Investigating hemodynamic parameters in a group of 19 ICU-patients with septic shock, respiratory variation of carotid doppler peak velocity (∆CDPV) has been shown to be able to predict fluid responsi...
Eligibility Criteria
Inclusion
- Age 18-80 years
- written informed consent
- scheduled major abdominal surgery
Exclusion
- Age \<18 or \>80 years
- pregnancy
- SIRS or sepsis
- any kind of cardiac arrhythmia
- known valve disease
- known heart failure
- any kind of known carotid stenosis
- carotid doppler peak velocity \>182 cm/s before baseline measurement (expected stenosis)
- missing indication for invasive arterial blood pressure monitoring (IBP) not related to the study
- peripheral artery disease (PAD)
- BMI \> 35 kg/m2
- intraabdominal hypertension
- ASA-PSC of 4
- severe lung disease (e.g. COPD grade 3, fibrosis)
- esophageal disease of any kind
- participation in another clinical study
Key Trial Info
Start Date :
January 11 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2025
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT05185141
Start Date
January 11 2022
End Date
April 1 2025
Last Update
October 3 2024
Active Locations (1)
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1
Department of Anesthesiology, Johannes-Gutenberg University Medical Center
Mainz, Rhineland-Palatinate, Germany, 55131