Status:

COMPLETED

Visa-versa! Breaking Instead of Pushing the Pedals-B

Lead Sponsor:

University of Zurich

Conditions:

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Eccentric muscle work is defined as lengthening of a muscle while applying force. It was shown that with eccentric work, muscles are able to perform four times as much power compared to usual concentr...

Detailed Description

Eccentric muscle work is when a muscle lengthens while applying force. Although eccentric muscle work is part of everyday life, e.g. whilst descending, it is not integrated in modern training protocol...

Eligibility Criteria

Inclusion

  • In a stable condition on the same disease specific medication \>4 weeks.
  • Signed informed consent.
  • Patients with chronic obstructive pulmonary (COPD) with a FEV1/FVC-ratio \> 0.7

Exclusion

  • Severe daytime hypoxemia (pO2 ≤7.3 kPa or \<55 mmHg).
  • Other clinically significant concomitant disease states (e.g., renal, hepatic dysfunction, etc.).
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorder, dementia or confusional state of the subject, neurological or orthopedic problems with inability to ride a bicycle.
  • Woman with known pregnancy (Women with known pregnancy will not be allowed into the study. It will however not be searched for early unknown pregnancy in woman of child-bearing potential, as cycling is not contraindicated in early unknown pregnancy stage and we thus do not plan routine pregnancy tests before study entrance in women of childbearing potential).
  • Enrolment into another clinical trial with active treatment.

Key Trial Info

Start Date :

November 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2024

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT05185856

Start Date

November 15 2023

End Date

May 31 2024

Last Update

January 23 2025

Active Locations (1)

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1

Respiratory Clinic, University Hospital of Zurich

Zurich, Canton of Zurich, Switzerland, 8091