Status:
UNKNOWN
The Effect of iTBS on the Inhibition Control Function of BN
Lead Sponsor:
Shanghai Mental Health Center
Conditions:
Feeding and Eating Disorders
Eligibility:
FEMALE
18-35 years
Phase:
NA
Brief Summary
Pathological out-of-control behavior is the core clinical symptom of Bulimia nervosa (BN). The study of its neural circuits and biological mechanism is very important to explore new intervention targe...
Detailed Description
Bulimia nervosa(BN) is a chronic and refractory mental disorder characteristic of recurrent binge eating and weight control which mostly occur in adolescents and young women. The life-time prevalence ...
Eligibility Criteria
Inclusion
- female,
- Han nationality;
- right-handed;
- meet the diagnostic criteria of DSM-5 bulimia nervosa, body mass index (BMI) ≥ 18.5kg / m2;
- education level of junior high school or above, sufficient audiovisual level to complete the necessary examination of the study.
- Before entering the group, he has received fluoxetine treatment, the dose has been stable for one month, and has not received any form of physiotherapy (such as electroconvulsive therapy) within one month;
- each patient must understand the nature of this study and sign an informed consent form.
Exclusion
- Patients who meet the diagnosis of DSM-5 other than BN, such as substance abuse / dependence, bipolar disorder, high risk of suicide, strong destructive impulses or antisocial behaviors;
- complicated with severe organic diseases and cognitive impairment, make it impossible for patients to complete the required symptom assessment and psychological tests;
- have a history of brain trauma or brain disease, epilepsy, etc. Those who have been exposed to ECT or MECT within 1 month;
- those with intracranial metal materials or pacemakers, implanted metal objects in vivo;
- those who are pregnant or planned pregnancy, women of childbearing age who are positive in pregnancy test.
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2023
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05186441
Start Date
July 1 2020
End Date
June 30 2023
Last Update
January 11 2022
Active Locations (1)
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1
Shanghai Mental Health Center
Shanghai, Shanghai Municipality, China, 200030