Status:
UNKNOWN
Treatment of Postoperative Hypoparathyroidism Using Cultured Allogenic Parathyroid Cells
Lead Sponsor:
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Collaborating Sponsors:
Belarusian State Medical University
Conditions:
Postoperative Hypoparathyroidism
Eligibility:
All Genders
18-70 years
Phase:
PHASE1
PHASE2
Brief Summary
The idea of the project is to develop a method of treatment of postoperative hypoparathyroidism using cultured allogenic parathyroid cells.
Detailed Description
The cells will be isolated and cultured from the parathyroid gland of brain-dead organ donors. Cells will be tested for the immunophenotype, viability, sterility and the production of parathyroid horm...
Eligibility Criteria
Inclusion
- Clinical diagnosis of postoperative hypoparathyroidism
- Decreased PTH concentrations in blood serum
- The patient can read, understand, follow the examination procedures and complete, if necessary, the required documentation
- Written informed consent
Exclusion
- The presence of any malignant tumor within the last 5 years
- Acute or chronic diseases in the stage of decompensation
- Chronic infectious diseases: HIV, viral hepatitis B, C, tuberculosis
- Patients who are pregnant, breastfeeding, or fertile patients who are not using adequate contraceptive methods
- Chronic and protracted mental disorders, all diseases with the presence of the syndrome of dependence on alcohol, drugs and psychoactive substances, any other condition that makes the patient unable to understand the nature, extent and possible consequences of the study or, in the opinion of the researcher, prevents the patient from observing and performing protocol
- Patients are unable or unwilling to give written informed consent and / or follow research procedures
- Any other medical condition that, in the opinion of the investigator, may be associated with an increased risk to the patient or may affect the outcome or evaluation of the study
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05186883
Start Date
March 1 2022
End Date
December 31 2023
Last Update
January 13 2022
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.