Status:

RECRUITING

Safety and Efficacy of SBRT in the Reirradiation for Ultra-central Thoracic Malignant Tumors

Lead Sponsor:

Peking University Third Hospital

Conditions:

Stereotactic Body Radiation Therapy

Irradiation; Reaction

Eligibility:

All Genders

18-80 years

Brief Summary

The reirradiation of thoracic tumor is difficult. The possibility of surgery or re course radiotherapy is very small. In the NCCN guideline, only systemic treatment is recommended. However, the effect...

Eligibility Criteria

Inclusion

  • Pathological diagnosis is malignant tumor.
  • The location of the target lesion belongs to the ultra-central type of chest.
  • The target lesion had a history of radiotherapy, and the lesion diameter is ≤ 5cm.
  • There is no extensive systemic metastasis or although there is metastasis, the metastasis have been controlled by previous treatment.
  • KPS\>70, no serious or uncontrolled underlying diseases, such as severe or uncontrolled hypertension, diabetes, cardiovascular and cerebrovascular diseases and organ dysfunction, and patients are expected to be tolerated by radiotherapy.

Exclusion

  • Poor basic pulmonary function or symptom correlation caused by various reasons, unable to lie flat or cooperate with treatment.
  • The general condition is poor, and the expected survival time is less than 3 months.
  • Psychiatric patients or poor compliance, unable to cooperate to complete treatment.
  • For other reasons, the researcher believes that it is not suitable to participate in this trial.

Key Trial Info

Start Date :

May 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 30 2027

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05189054

Start Date

May 1 2022

End Date

April 30 2027

Last Update

December 27 2023

Active Locations (1)

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Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191