Status:
COMPLETED
Hormonal Monitoring and Progesterone Adjustment in Frozen Embryo Transfer Cycles
Lead Sponsor:
Alexandria University
Conditions:
Female Infertility
Eligibility:
FEMALE
20-42 years
Phase:
NA
Brief Summary
Hormonal monitoring impact on overall pregnancy rate in frozen embryo transfer (FET)cycles and hence progesterone supplement adjustments remain debatable in current literature. This prospective random...
Detailed Description
Progesterone (P4) is a steroidal hormone that is required for successful embryo implantation and maintenance of the pregnancy in natural cycles, fresh in vitro fertilization cycles, and frozen embryo ...
Eligibility Criteria
Inclusion
- Age of female patient 42 years or less
- Normal uterine cavity
- All embryos are day 5 or day 6 frozen blastocysts
Exclusion
- History of recurrent implantation failure
- Previously known major thrombophilia factors
- Non-compliance to given protocol
- Endometrial thickness \< 7mm after 13 days of priming with estradiol valerate
- pre-existing metabolic diseases (Diabetes Mellitus \& Hypertension).
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2021
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT05189145
Start Date
October 1 2019
End Date
October 1 2021
Last Update
February 2 2024
Active Locations (1)
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1
Infertility Center
Alexandria, Egypt