Status:
RECRUITING
Cardiopulmonary Bypass Induced Red Blood Cell Lysis
Lead Sponsor:
University of Maryland, Baltimore
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Cardiopulmonary Bypass
Cardiac Surgery
Eligibility:
All Genders
18-88 years
Brief Summary
Studying the dynamics of red blood cell lysis, pfH, protective proteins and organ injury, limits will be set for safe levels of pfH following the use of CPB. These results will be compared to existing...
Detailed Description
Cost estimates for brain, lung, cardiac, and kidney complications following complex cardiac surgeries that require a medical assist device to by-pass the heart and lungs (cardiopulmonary bypass, CPB) ...
Eligibility Criteria
Inclusion
- Admitted to UMMC for cardiac procedure
- Age: \>/=18 y.o TO 88 y.o.
- Undergoing CPB \>1hr for the following surgeries (a) complex cardiac surgery (b) heart valve replacement surgery OR (c) CABG surgery.
Exclusion
- Pregnant
- Non English speaking
- Unable to consent or have Legally Authorized Representative (LAR) assent to study
Key Trial Info
Start Date :
March 22 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05189262
Start Date
March 22 2022
End Date
December 1 2027
Last Update
August 19 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Center for Blood Oxygen Transport and Hemostasis
Baltimore, Maryland, United States, 21201