Status:
RECRUITING
Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms?
Lead Sponsor:
Royal Free Hospital NHS Foundation Trust
Collaborating Sponsors:
Private Physiotherapy Education Fund
Conditions:
Neuromuscular Diseases
Eligibility:
All Genders
18+ years
Brief Summary
Objectives: * To establish if physiotherapists can use the waveform traces from the cough assist machine to work out when patients are having an abnormal airway response to cough assist * To establis...
Eligibility Criteria
Inclusion
- Patients with neuromuscular disease(NMD) including but not limited to Motor Neurone Disease (MND), Multiple Sclerosis (MS) and Muscular Dystrophy
- Age ≥18
Exclusion
- Unable to comply with protocol
- Unable to give informed consent
- Evidence of obstructive airways disease FEV1:FVC \<0.7
- Patients with a history of:
- Un-drained pneumothorax
- Severe bronchospasm
- Head injury with ICP \> 25mmHg
- Severe arterial hypotension
- Trache-oesophageal fistula
- Significant haemoptysis
- Facial fractures
- Vomiting
- Flail segment
- Epistaxis within two weeks
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05189600
Start Date
January 1 2022
End Date
January 1 2025
Last Update
June 13 2024
Active Locations (1)
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1
Royal Free London NHS foundation Trust
London, United Kingdom, NW3 2QG