Status:

COMPLETED

An Extension Study for Participants Who Have Completed the Treatment Period of a Qualifying Parent Study

Lead Sponsor:

Pfizer

Conditions:

Dermatomyositis

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

The purpose of this research study is to evaluate the long-term safety, and tolerability of PF-06823859 study drug in adult participants with Dermatomyositis (DM) from a qualifying study.

Eligibility Criteria

Inclusion

  • Participants aged ≥18 and ≤80 with moderate to severe dermatomyositis (DM), that have completed the treatment period of a qualifying study.
  • Capable of giving signed informed consent.
  • Participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures.

Exclusion

  • Other medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study
  • Participants who met discontinuation criteria at any point during the participating qualifying studies.
  • Participants with an ongoing safety event in the qualifying studies which, in the opinion of the investigator or sponsor, is an ongoing safety concern OR the participant has met safety monitoring criteria in the qualifying study that has not resolved.

Key Trial Info

Start Date :

December 20 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 20 2023

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT05192200

Start Date

December 20 2021

End Date

November 20 2023

Last Update

February 6 2025

Active Locations (25)

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Page 1 of 7 (25 locations)

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35233

2

University of Alabama at Birmingham, Department of Dermatology

Birmingham, Alabama, United States, 35294

3

Mayo Clinic

Scottsdale, Arizona, United States, 85259

4

Attune Health Research Inc.

Beverly Hills, California, United States, 90211