Status:
COMPLETED
Evaluation of the Regeneration Capacity of Satellite Cells From the Quadriceps Compared to That of the Diaphragm
Lead Sponsor:
University Hospital, Montpellier
Conditions:
Diaphragm Injury
Mechanical Ventilation Complication
Eligibility:
All Genders
30-80 years
Phase:
NA
Brief Summary
Actually no treatment exists to prevent the loss of diaphragmatic function induced by mechanical ventilation during an intensive care unit stay. The consequence is a growing number of survivors with m...
Detailed Description
This study focuses on mechanical ventilation used in intensive care unit to supplement ventilatory function in patients. Indeed, mechanical ventilation can "paradoxically" be at the origin of complica...
Eligibility Criteria
Inclusion
- age between 30 and 80 years old
- patient treated by the digestive surgery department of Montpellier University Hospital for a benign or malignant tumor of the liver requiring surgical excision in contact with the diaphragm who agreed to participate in the BOTAN study (Approval Number assigned by the IRB of Montpellier : 2021\_IRB-MTP\_08-37)
- patient clinically stable at the time of the study, ie not requiring any treatment
Exclusion
- Patients undergoing treatment with antibiotics or corticosteroids, or recently within the last 4 months
- Pregnant or breastfeeding woman.
- Patients with a body mass index \> 30
- Patients with any criteria that may in themselves impair respiratory muscle function such as chronic obstructive pulmonary disease, heart failure, systemic infection, neuromuscular pathology, psychiatric pathology or metabolic disorder.
- Patients with coagulopathy or thrombocytopenia.
Key Trial Info
Start Date :
February 18 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2024
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT05194631
Start Date
February 18 2022
End Date
May 30 2024
Last Update
December 6 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital
Montpellier, France, 34295