Status:

UNKNOWN

Quantifying Viral Load in Respiratory Particles That Are Generated by Children and Adults With COVID-19 Infection

Lead Sponsor:

Massachusetts General Hospital

Conditions:

COVID-19

Eligibility:

All Genders

Phase:

NA

Brief Summary

The study will be a prospective cohort design to determine if children generate aerosols that harbor a viral load similar to adults. Prior to beginning enrollment, researchers may recruit up to 10 par...

Detailed Description

For children and adults who are admitted to MGH, study staff will perform: Step 1: A nasal and oral swab will be obtained to establish the nasopharyngeal viral load. Step 2: Study staff will use the...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • SARS-CoV-2 PCR positive in the last fourteen days
  • Symptomatic with typical symptoms of COVID-19, including fever, cough, nasal congestion, rhinorrhea, anosmia, ageusia, shortness of breath, chest pain, fatigue, myalgias, or other atypical symptoms with documentation of that symptom OR
  • Asymptomatic with laboratory confirmation of cycle threshold value \< 30.
  • Exclusion criteria:
  • Chronic respiratory disease or neuromuscular condition associated with severely reduced lung function defined as FEV1 or FVC \<50% predicted, or requiring chronic supplemental oxygen or respiratory support
  • On current respiratory support via supplemental oxygen, non-invasive ventilation, or invasive mechanical ventilation

Exclusion

    Key Trial Info

    Start Date :

    January 13 2022

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 1 2022

    Estimated Enrollment :

    30 Patients enrolled

    Trial Details

    Trial ID

    NCT05195229

    Start Date

    January 13 2022

    End Date

    May 1 2022

    Last Update

    February 15 2022

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Massachusetts General Hospital

    Boston, Massachusetts, United States, 02114