Status:

COMPLETED

Distinguishing Participant Groups Using Autonomic Dysfunction

Lead Sponsor:

DyAnsys, Inc.

Conditions:

Diabetes

Eligibility:

All Genders

18-85 years

Brief Summary

A study population with impaired fasting glucose levels, impaired glucose tolerance levels and diabetes (with or without complications) along with healthy patients will be chosen as participants. Thei...

Detailed Description

The Autonomic Nervous System (ANS) is a fundamental part of the nervous system in the body. And yet, there is no technique to test or measure the health and functioning of a person's autonomic nervous...

Eligibility Criteria

Inclusion

  • Able to provide informed consent
  • Age between 18 to 85
  • Body Mass Index (BMI) between 25 and 40 kg/m2
  • Individuals with normal glucose levels, pre-diabetes and diabetes Type 2 for at least 1 year (diagnosed by ADA criteria) and up to 20 years
  • Stable dose of meds for 3 months
  • Stable diet and lifestyle for 3 months
  • Medical history without clinically significant abnormalities

Exclusion

  • Have a disorder that would impede performing the HRV measurement procedure (i.e., abnormal cardiac rhythm, heart disease, including coronary artery disease, angina, and arrhythmia, cardiac pacemaker, stroke, panic attack, cognitive impairment, renal failure)
  • Chronic disease (e.g. HIV, Cushing syndrome, CKD, acromegaly, active hyperthyroidism etc.)
  • Cancer and anticancer treatment in the last 5 years
  • Pregnancy or lactation
  • Subjects with major physical disability
  • Subjects with previous history of cerebrovascular accident
  • Any disorder, which in the investigator's opinion might jeo

Key Trial Info

Start Date :

November 17 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 29 2022

Estimated Enrollment :

175 Patients enrolled

Trial Details

Trial ID

NCT05199350

Start Date

November 17 2021

End Date

July 29 2022

Last Update

October 10 2023

Active Locations (1)

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Sri Rachandra Institute of HigherEducation And Research

Chennai, Tamil Nadu, India, 600116