Status:
COMPLETED
Improving Sleep and Cognition in Alzheimer's Disease
Lead Sponsor:
Emory University
Collaborating Sponsors:
National Institute on Aging (NIA)
Emory Goizueta Alzheimer's Disease Research Center (ADRC)
Conditions:
Alzheimer Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Cognitive disorders include such things as memory disorders, mild cognitive impairment, and Alzheimer's disease (AD). The purpose of the study is to learn more about whether a dietary citicoline suppl...
Detailed Description
The research team will test these hypotheses via a randomized, double-blind, placebo-controlled pilot study of citicoline in individuals with AD. Participants will be recruited from the Alzheimer's Di...
Eligibility Criteria
Inclusion
- Participants who are diagnosed with AD and confirmed from the medical record.
- At least 18 years of age living within the continental United States
- Read and understand English
- Have Internet and email access (this criterion applies to the legally authorized representatives)
Exclusion
- No telephone access
- Epilepsy or head trauma resulting in unconsciousness in the past two years
- Presence of chronic obstructive pulmonary disease, asthma, severe cardiac insufficiency (congestive heart failure, myocardial infarction), type I diabetes, vitamin B12 or folic acid deficiency, liver cirrhosis, thyroid dysfunction, rheumatoid arthritis, chronic renal failure, and/or psychiatric disorders, obstructive sleep apnea, restless legs syndrome or periodic limb movement disorder
- History of alcohol dependence and medication abuse
- Night shift workers or those in situations where they regularly experience jet lag, or have irregular work schedules, since circadian misalignment may alter markers of inflammation
Key Trial Info
Start Date :
July 27 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 21 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05200208
Start Date
July 27 2022
End Date
September 21 2025
Last Update
December 1 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Emory University School of Nursing
Atlanta, Georgia, United States, 30322
2
Goizueta Alzheimer's Disease Research Center
Atlanta, Georgia, United States, 30329