Status:
RECRUITING
Interventions in Mathematics and Cognitive Skills
Lead Sponsor:
Stanford University
Collaborating Sponsors:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Math Learning Disability
Child Development
Eligibility:
All Genders
6-12 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including tho...
Detailed Description
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including tho...
Eligibility Criteria
Inclusion
- Elementary school aged children starting from first grade (6-12 years old)
- IQ: Participants with a Full Scale IQ \> 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).
- Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests
- Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests
- Normal or corrected-to-normal vision and no hearing impairments
- Inclusion in MRI scan session: Right-handed
Exclusion
- History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)
- History of trauma involving head injury
- Consistent psychiatric medications
- Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)
Key Trial Info
Start Date :
May 5 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT05201534
Start Date
May 5 2023
End Date
June 30 2026
Last Update
August 15 2025
Active Locations (1)
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1
Stanford Cognitive and Systems Neuroscience Laboratory
Palo Alto, California, United States, 94304