Status:
UNKNOWN
Efficacy and Safety of Butorphanol Tartrate Injection for the Patients With Mechanical Ventilation
Lead Sponsor:
Shanghai Zhongshan Hospital
Conditions:
Analgesia
Hospital-acquired Infections
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To compare the incidence of hospital-acquired infections between butorphanol and fentanyl.
Detailed Description
Butorphanol can improve inflammation and promote the recovery of pro-inflammatory/anti-inflammatory cytokine balance.However, there is still a lack of relevant clinical studies on butorphanol and fent...
Eligibility Criteria
Inclusion
- need mechanical ventilation for more than 48 hours
- more than 18 years old
- without hospital-acquired infection before admission to ICU
- volunteer to participate in this study
Exclusion
- allergic or contraindicated to the drug
- severe cardiac insufficiency, conduction block and bradycardia
- recent use of analgesic, sedative and antidepressant drugs
- psychiatric or neurological diseases or neurosurgery-related diseases
- history of steroid cortisol and immunosuppressants
- severe liver dysfunction or renal dysfunction
- pregnancy
- refuse to enrollment
Key Trial Info
Start Date :
January 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05201560
Start Date
January 1 2022
End Date
January 1 2023
Last Update
January 21 2022
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