Status:

SUSPENDED

Effect of Multielectrode Versus Point-by-Point Mapping on Recurrence of Ventricular Tachycardia in Ischemic Heart Disease

Lead Sponsor:

Helios Health Institute GmbH

Conditions:

Ventricular Tachycardia

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

VT ablation is a frequently performed intervention in patients with symptomatic ventricular tachycardia, electrical storm due to monomorphic VT and appropriate ICD shocks, primarily aiming at reducing...

Detailed Description

Catheter Ablation in Patient with VT and ischemic heart disease has shown a beneficial effect in terms of VT Recurrence and Quality of life. The short-term outcome of catheter Ablation in Patients wit...

Eligibility Criteria

Inclusion

  • Age ≥18 years.
  • Symptomatic ventricular tachycardia with/without ICD and underlying ischemic
  • No need for coronary revascularisation therapy based on coronary angiography or Cardiac MRI
  • Class I or IIa indication for catheter ablation (according to 2015 Guidelines of the European Society of Cardiology for the management of ventricular tachycardias).
  • Signed informed consent.

Exclusion

  • Patients with ventricular assist device
  • Reversible causes of ventricular tachycardia (e. g. thyroid disorder, acute alcohol intoxication, recent major surgical procedures, trauma or acute infection/acute myocarditis)
  • Recent cardiovascular event including myocardial infarction, percutaneous intervention, valve or cardiac bypass surgery
  • Previous VT ablation within the last 3 months
  • Patients with ventricular tachycardia and known atrial fibrillation with sufficient antiarrhythmic drug therapy regarding rhythm control of atrial fibrillation
  • Medical conditions limiting the expected survival to \< 1 year
  • On the waiting list for heart transplant.
  • Participation in any other randomized controlled trial
  • Women of childbearing potential without appropriate contraceptive measures (oral contraceptives, vaginal ring, intrauterine devices, implanon, injections, partner with vasectomy)
  • Subjects under legal supervision or guardianship
  • Unable to give informed consent

Key Trial Info

Start Date :

October 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2024

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT05203484

Start Date

October 1 2022

End Date

July 30 2024

Last Update

August 19 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Herzzentrum Leipzig

Leipzig, Saxony, Germany, 04289