Status:
RECRUITING
Visa-versa! Breaking Instead of Pushing the Pedals-C
Lead Sponsor:
University of Zurich
Conditions:
Left Heart Failure
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Eccentric muscle work is defined as lengthening of a muscle while applying force. It was shown that with eccentric work, muscles are able to perform four times as much power compared to usual concentr...
Detailed Description
Eccentric muscle work is when a muscle lengthens while applying force. Although eccentric muscle work is part of everyday life, e.g. whilst descending, it is not integrated in modern training protocol...
Eligibility Criteria
Inclusion
- In a stable condition on the same disease specific medication \>4 weeks.
- Signed informed consent.
- Patients with left-heart disease
Exclusion
- Severe daytime hypoxemia (pO2 ≤7.3 kPa or \<55 mmHg).
- Other clinically significant concomitant disease states (e.g., renal, hepatic dysfunction, etc.).
- Inability to follow the procedures of the study, e.g. due to language problems, psychological disorder, dementia or confusional state of the subject, neurological or orthopedic problems with inability to ride a bicycle.
- Woman with known pregnancy (Women with known pregnancy will not be allowed into the study. It will however not be searched for early unknown pregnancy in woman of child-bearing potential, as cycling is not contraindicated in early unknown pregnancy stage and we thus do not plan routine pregnancy tests before study entrance in women of childbearing potential).
- Enrolment into another clinical trial with active treatment.
Key Trial Info
Start Date :
June 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05204693
Start Date
June 1 2025
End Date
December 31 2025
Last Update
June 13 2025
Active Locations (1)
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1
Respiratory Clinic, University Hospital of Zurich
Zurich, Canton of Zurich, Switzerland, 8091