Status:
RECRUITING
HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Cirrhosis
End Stage Liver DIsease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.
Eligibility Criteria
Inclusion
- Adult patients ≥ 18 years old with diagnosis of cirrhosis based on histology, radiology, and/or elastography presenting to the emergency department or inpatient general medicine service
- Patients must have one of the following:
- Ascites (requiring diuretics or serial large volume paracenteses)
- Hepatic hydrothorax (requiring diuretics)
- Hepatic encephalopathy (requiring medications)
Exclusion
- All existing MGB home hospital criteria apply, with the following taking precedent for this specific condition
- History of solid organ transplantation
- On hemodialysis
- MELD score \> 20
- Score \<10 on Simplified Animal Naming Test (S-ANT1)
- Current admission for hemodynamically significant GI bleeding or alcohol withdrawal
- Require routine administration of controlled substances
- Those deemed ineligible based on the MGH Home Hospital, inpatient medicine or hepatology clinician evaluation
Key Trial Info
Start Date :
July 21 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05205954
Start Date
July 21 2025
End Date
December 31 2026
Last Update
July 24 2025
Active Locations (2)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114