Status:
COMPLETED
Bioenhancing Effects of Black Pepper With Turmeric on Pain Ratings
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
McCormick Science Institute
Conditions:
Pain
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Although multiple clinical trials have been reported studying the effects of turmeric and turmeric-derived curcuminoid containing extract on pain by various study designs (including both acute and chr...
Eligibility Criteria
Inclusion
- Age: 40 or older
- BMI: 20-40
- Diet: No dietary prohibitions/allergies
- 21-day availability
- Moderate Pain Rating (self-reported numeric rating 4-7 on 10 pt scale)
Exclusion
- Turmeric or Black Pepper Allergy, or any allergy that would prevent menu item selections for 7 days of feeding
- Recent change in pain levels - e.g. acute injury
- Known eating disorder
- No access to a phone capable of text message, electronic device (phone, tablet, computer/laptop) with email and internet access
- Inability to continue on protocol for 3 consecutive weeks.
- Medical conditions (cardiovascular disease event within the past six months, severe pulmonary disease, renal failure, major liver dysfunction within the last 2 years, digestive disorders including gastric reflux, irritable bowel disease, Crohn's disease or related conditions current smoker or recently quit less than 6 months prior) or medications that would prevent the ability to comply with treatment assignment (e.g. blood thinners, arrhythmia control medications, prescription narcotic pain medications).
- Use of estrogen or testosterone replacement therapy within the past 6 months,
- Current use of oral corticosteroids \> 5 days/month on average
- Cold, flu, virus, allergy or other conditions that impairs sensory perceptions (taste and smell) which may impact protocol compliance
- COVID19 positive status at time of enrollment
- Consumes an average of ≥1 serving of turmeric per day, or has never consumed and/or would not be willing to consume turmeric
- Consumes black pepper ≥ 3 servings per day and/or would not be willing to abstain from pepper consumption for the prescribed days during the study
- Abstinence from or dislike of either turmeric or black pepper
- Dependence on others for food procurement and preparation
Key Trial Info
Start Date :
February 13 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 16 2023
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05206266
Start Date
February 13 2022
End Date
June 16 2023
Last Update
July 5 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294