Status:

RECRUITING

The ACCESSIT Study

Lead Sponsor:

Unity Health Toronto

Conditions:

Respiratory Support

Eligibility:

All Genders

16+ years

Brief Summary

The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord...

Detailed Description

In patients with spinal cord injury, separation from mechanical ventilation is an essential aspect of the prognosis. Denervation of specific muscles, as a consequence of the injury, can generate a dys...

Eligibility Criteria

Inclusion

  • Presence of traumatic spine lesion (with and without spinal cord injury)
  • Requiring invasive mechanical ventilation, via oro-tracheal or tracheostomy tube,
  • 16 years of age or older
  • Patient or substitute decision maker able to provide consent

Exclusion

  • Expected withdrawal of treatments within 24 hours of screening
  • Chronic respiratory failure already treated with mechanical ventilation before the injury
  • Documented pre-existing neuromuscular diseases

Key Trial Info

Start Date :

December 17 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05207046

Start Date

December 17 2021

End Date

June 1 2026

Last Update

May 20 2025

Active Locations (1)

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Unity Health Toronto - St. Michael's Hospital

Toronto, Ontario, Canada, M5B 1T8