Status:
COMPLETED
Effects of Canola Oil and Coconut Oil on Postprandial Metabolism in Older Adults With Increased Cardiometabolic Risk
Lead Sponsor:
University of Bonn
Collaborating Sponsors:
Union for the Promotion of Oil and Protein Plants (UFOP, Germany)
Conditions:
Cardiovascular Diseases
Metabolic Syndrome
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
The aim of this study is to investigate the postprandial effects of fat content and fatty acid composition of mixed meals on parameters associated with cardiometabolic diseases. Therefore, older subje...
Detailed Description
In a crossover design, 30 older men and women with increased risk of cardiometabolic diseases consume 4 mixed meals, enriched with either 25 or 50 g canola or coconut oil. During a postprandial period...
Eligibility Criteria
Inclusion
- BMI: 27 - 34,9 kg/m2
- Waist circumference: women ≥ 80 cm, men ≥ 94 cm
- At least two of the following criteria of metabolic syndrome:
- Fasting triglycerides in serum: ≥ 150 mg/dl Fasting HDL-Cholesterol in serum: women \< 50 mg/dl, men \< 40 mg/dl Systolic blood pressure: ≥ 130 mmHg, diastolic blood pressure: ≥ 85 mmHg Fasting glucose in plasma: ≥ 100 mg/dL
Exclusion
- Smoking
- Diseases that may impact outcome measures (e.g., thyroid diseases, insulin-dependent diabetes mellitus, impaired renal function, tumors, anemia)
- Intake of immunosuppressives or supplements (e.g., fish oil)
- Participation in another study
Key Trial Info
Start Date :
March 9 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 18 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05208346
Start Date
March 9 2022
End Date
October 18 2022
Last Update
April 29 2025
Active Locations (1)
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1
University of Bonn
Bonn, Germany, 53115