Status:
COMPLETED
Flexible Representation of Speech
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institutes of Health (NIH)
Carnegie Mellon University
Conditions:
Epilepsy
Eligibility:
All Genders
15-25 years
Phase:
NA
Brief Summary
The overarching goal of this exploratory research is to understand the dynamic and flexible nature of speech processing in the human supratemporal plane. The temporal lobe has long been established as...
Detailed Description
The purpose of this study is to understand the dynamic, flexible nature of speech processing as a function of perceptual weight applied to acoustic-phonetic dimensions within varying listening context...
Eligibility Criteria
Inclusion
- Individuals 15-25 years old
- Undergoing sEEG placement in the supratemporal plane for clinically necessary localization of epileptic foci or language mapping
- Fluent English speakers
- Cognition and speech-language skills within normal limits (as determined by evaluation prior to surgery)
- Normal or correct-to-normal visual acuity
- Normal hearing acuity in each ear (as determined by audiometric assessment)
- No history of autism or ADHD
Exclusion
- Individuals with intellectual disabilities
- Abnormal epileptiform activity in the supratemporal plane
- Lack of fluent English comprehension/production
- Severe language or auditory-specific cognitive dysfunction
- History of autism or ADHD
Key Trial Info
Start Date :
May 2 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 10 2025
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT05209386
Start Date
May 2 2022
End Date
April 10 2025
Last Update
September 8 2025
Active Locations (1)
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1
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15224