Status:
UNKNOWN
Impact of Closely Grouped, Iterative Exposures to Suxamethonium During ECT on the Sensitization to NMBA and the Development of Protective Antibodies
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Depression
Mania
Eligibility:
All Genders
18+ years
Brief Summary
Acute per-anesthetic hypersensitivity reaction (HSA-PA) is a rapidly occurring systemic reaction following injection of a drug during anesthesia (mortality between 3 and 9%). The substances responsibl...
Detailed Description
Acute per-anesthetic hypersensitivity reaction (HSA-PA) is a rapidly occurring systemic reaction following injection of a drug during anesthesia (mortality between 3 and 9%). The substances responsibl...
Eligibility Criteria
Inclusion
- Patient requiring iterative exposure to ECT as part of their psychiatric pathology in one of the investigator center
- Patient who has not had ECT in the last 10 years for the phase E group, regardless of their previous ECT exposure for the phase P group
- Patient who has been informed and has signed the consent form
Exclusion
- Absence of written informed consent
- Allergies identified specifically to Neuro-Muscular Blocking Agents (NMBA)
- Patient under tutelage, curatorship or judicial protection
- Patient without social security
- Contraindication to ECT : intracranial hypertension, intracranial lesions without intracranial hypertension, recent episode of cerebral hemorrhage, recent myocardial infarction or embologenic disease, presence of aneurysms or vascular malformations at risk of hemorrhage, retinal detachment, pheochromocytoma, history of ineffective treatment with ECT having had serious side effects, taking anticoagulant treatments
Key Trial Info
Start Date :
January 27 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2023
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT05210062
Start Date
January 27 2022
End Date
September 1 2023
Last Update
April 12 2022
Active Locations (1)
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1
Saint-Antoine Hospital
Paris, France, 75012