Status:

UNKNOWN

Research on Prevention, Intervention and Mechanisms of Obesity and Its Comorbidities

Lead Sponsor:

Slovak Academy of Sciences

Collaborating Sponsors:

Medical University of Vienna

Conditions:

Obesity

Exercise

Eligibility:

All Genders

25-45 years

Phase:

NA

Brief Summary

Obesity and lack of physical activity are associated with an increased risk of many chronic diseases and accelerate the processes associated with aging. Weight reduction and physical fitness are healt...

Detailed Description

Training is combining one 60min session of aerobic training with two 1-hour weekly lessons of aerobic strength training composed of 25 minutes, 60-70% 1RM, training the large muscle groups and 25 minu...

Eligibility Criteria

Inclusion

  • sedentary men and women (approximately 1:1) aged 25-45 years, BMI 28-38 kg/m2
  • absence of chronic diseases and regular pharmacotherapy intake
  • capable to complete a training intervention (assessment by a cardiologist)
  • signed informed consent
  • absence of any psychological, sociological or geographical factors that could jeopardize participation in the study
  • Vaccination against SARS-CoV-2 with one of the approved vaccines available in Slovakia (at least 2 weeks after the last dose) and regular PCR testing during the study.

Exclusion

  • any chronic disease (oncological, cardiovascular, neurological, liver, kidney or other diseases and its acute complications at the discretion of the doctor);
  • No cooperation of probands;
  • insufficient functional capacity - the presence comorbidities or disorders of the musculoskeletal system, which makes it impossible to complete the training program (assessment by cardiologist, or orthopedist or other specialist);
  • smoking, alcohol or drugs abuse;
  • non-compliance with epidemiological measures;
  • absence of complete vaccination with SARS-CoV-2 vaccine;
  • presence of a pacemaker or metal implants (contraindication for magnetic resonance imaging).

Key Trial Info

Start Date :

November 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05211817

Start Date

November 1 2021

End Date

December 31 2023

Last Update

January 27 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Biomedical Research Center Slovak Academy of Sciences

Bratislava, Slovakia, 84505