Status:

UNKNOWN

Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries

Lead Sponsor:

Jodi Stookey

Conditions:

Caries

Metabolomic Profile

Eligibility:

All Genders

5-10 years

Phase:

NA

Brief Summary

Saliva insulin shows promise as a non-invasive biomarker of high carbohydrate intake and/or insulin resistance, key risk factors for metabolic dysregulation and caries. Saliva insulin monitoring coul...

Detailed Description

This randomized controlled trial explores if saliva insulin is responsive to the kinds of obesity and caries intervention currently in progress in schools, namely drinking water intervention. The spe...

Eligibility Criteria

Inclusion

  • UCSF Pediatric Dental Clinic patients New patient exam or recall exams Caregiver and child speak English, Spanish or Chinese Ages 5-10 years San Francisco residents Non-acutely ill (healthy enough to attend school, no fever and no systemic conditions)

Exclusion

  • Child and caregiver do not speak English, Spanish or Chinese Not a San Francisco resident Under age 5 years Over age 10 years Child unwilling to accept randomized drink assignment Child unable or unwilling to drink water or apple juice Child unable or unwilling to give saliva Child is presenting to the dental clinic for an operative procedure Acute illness, fever, infection or condition that would prevent the child from attending school No remaining space in study group (weight-specific recruitment is complete).

Key Trial Info

Start Date :

October 12 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT05211843

Start Date

October 12 2022

End Date

December 1 2023

Last Update

April 13 2023

Active Locations (1)

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UCSF Pediatric Dentistry

San Francisco, California, United States, 94143