Status:

RECRUITING

Biological Markers for Post-Traumatic Stress Disorder

Lead Sponsor:

Assaf-Harofeh Medical Center

Conditions:

Post Traumatic Stress Disorder

Eligibility:

MALE

20-60 years

Brief Summary

The current study aims to evaluate the sensitivity and specificity of a combination of various objective biomarkers for the diagnosis of PTSD.

Detailed Description

PTSD affects a major fraction of military combatants and is also very common in the general population. Like other psychiatric conditions, the diagnosis of PTSD is currently based on an interview and ...

Eligibility Criteria

Inclusion

  • The willingness and ability to read, understand and sign an informed consent form.
  • Age 20-60 years.
  • A history of more than 2 years of combat service, and of at least one potentially life-threatening combat experience.
  • One year or more after the last combat experience.

Exclusion

  • Inability to attend scheduled clinic visits or comply with the study protocol
  • A history of traumatic brain injury or any other known brain pathology.
  • Substance use, except for prescribed cannabis, if it can be withheld for at least 24 hours prior to the study evaluation.
  • A current psychiatric disorder other than PTSD.
  • The inability to perform an awake brain MRI.

Key Trial Info

Start Date :

January 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT05213858

Start Date

January 1 2022

End Date

January 1 2026

Last Update

February 6 2024

Active Locations (1)

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Assaf-Harofeh Medical Center

Ramla, Israel, 70300